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Differentiation: IGF-1 is often described as a maturation factor because it can influence both proliferation and the differentiation of progenitor cells into specialized cell types

Although this impact in normal growth, strong evidence has been provided that IGF-1R is not an absolute requirement for normal growth, only partially (Baserga, 1999)

BMC Cancer 11 , 56 (2011)

For the low 1.6 mg dose, use 5 units per injection

Intramuscular injection near an injury site (a common self-administration approach) adds a theoretical local concentration benefit that has some support in animal wound models but has not been tested head-to-head against subcutaneous delivery in a controlled trial

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